Dr Mo Chen (BSc (Hons 1), PhD, is an exceptional early-career researcher (ECR) leader with an outstanding record of award-winning innovation and knowledge in the interdisciplinary field of biomedical engineering and medical biotechnology. His ground-breaking three-dimensional (3D) cell culture technology has shown immense promise in the area of spinal cord injury repair, with the potential impact of the technology recognized by the Research Australia Discovery Award 2020-2021. His supervisor is Professor James St John, head of the Clem Jones Centre for Neurobiology and Stem Cell Research. Mo Chen has a PhD in neuroscience about spinal cord injury repair and has seven years of experience and expertise in cell biology and medical bioengineering. This includes developing cell transplantation products to treat spinal cord injury and analyzing various 3D culture systems, such as low attachment 3D culture, mammalian cell culture with bioreactors, and hydrogel-based 3D culture. Chen's groundbreaking brain organoids technology, with two patents (Provisional patent number 2017904456 and 2017904064) for the root technology, and new patent applications are currently being prepared for the updated version. This new organoid technique is advantageous as it contains only cells and does not require any assistance from scaffolds, fibres, or supporting gels. His contributions to 3D cell culture are that he has broken through the limitations of traditional 3D cell production concepts and he is the first to apply cell self-organisation theory to pre-clinical research.