<em>AUS-mTBI Extend: An extended and innovative model to predict recovery for people with mild traumatic brain injury. </em> — The Association Specialists
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AUS-mTBI Extend: An extended and innovative model to predict recovery for people with mild traumatic brain injury. (21891)

Jemma Keeves 1 2 3 , Sarah Hellewell 1 3 , Rachel Singer 1 , Daniel Fatovich 4 5 , Fatima Nasrallah 6 , Stuart McDonald 7 , Elizabeth Armstrong 8 , Karen Caeyenberghs 9 , Karen Barlow 10 11 , Biswadev Mitra 2 12 , Trish Ratajczak 13 , Michael Makdissi 14 15 16 17 , Elena Chebkasova 18 19 20 , John Gilroy 21 , Patrick Kwan 2 7 22 , Nick Rushworth 23 , George Charalambous 24 , Kirsten Vallmuur 25 26 , Natasha Lannin 7 12 , Belinda Gabbe 2 , Jennie Ponsford 27 28 , Vicki Anderson 29 30 , Melinda Fitzgerald 1 3
  1. Curtin University, Perth, WA, Australia
  2. Pre-Hospital, Emergency and Trauma, School of Public Health and Preventative Medicine , Monash University, Melbourne, Victoria, Australia
  3. Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia
  4. Emergency Medicine, Royal Perth Hospital, Perth, WA, Australia
  5. Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Nedlands, WA, Australia
  6. Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia
  7. Department of Neurosciences, Central Clinical School, Monash University, Melbourne, VIC, Australia
  8. School of Medical and Health Sciences, Edith Cowan University, Perth, WA, Australia
  9. Cognitive Neuroscience Unit, School of Psychology, Deakin University, Melbourne, VIC, Australia
  10. Queensland Children's Hospital, Brisbane, QLD, Australia
  11. Centre for Children's Health Research, University of Queensland, Brisbane, QLD, Australia
  12. Alfred Health, Melbourne, VIC, Australia
  13. Murdoch University, Perth, WA, Australia
  14. Olympic Park Sports Medicine Centre, Melbourne, VIC, Australia
  15. Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia
  16. Latrobe University, Melbourne, VIC , Australia
  17. Australian Football League, Melbourne, VIC, Australia
  18. Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, Australia
  19. Centre for Adolescent Health, Murdoch Children’s Research Institute, Parkville, VIC, Australia
  20. National Drug Research Institute, Curtin University, Perth, WA, Australia
  21. Aboriginal and Torres Strait Islander Research, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia
  22. Department of Neurology, Alfred Health, Melbourne, VIC, Australia
  23. Brain Injury Australia, Sydney, NSW, Australia
  24. Curve Tomorrow, Melbourne, VIC, Australia
  25. Centre for Healthcare Transformation, Australian Centre for Health Services Innovation, Queensland University of Technology, Brisbane, QLD, Australia
  26. Jamieson Trauma Institute, Brisbane, QLD, Australia
  27. Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Melbourne, VIC, Australia
  28. Monash Epworth Rehabilitation Research Centre, Epworth Healthcare, Melbourne, VIC, Australia
  29. Clinical Sciences Research, Murdoch Children’s Research Institute, Melbourne, VIC, Australia
  30. Psychology Service, The Royal Children's Hospital, Melbourne, VIC, Australia

Understanding mild traumatic brain injury (mTBI) is a significant challenge in Australia and worldwide. At least one in five Australians will experience a mTBI over their lifetime, with approximately 180,000 cases reported each year. AUS-mTBI Extend aims to recruit 200 participants via three metropolitan Emergency Departments (Melbourne; Brisbane; Perth). Demographic, injury circumstance, health status, mTBI symptomology and care management data will be collected at the time of injury, with follow-up for 12-months or until symptom resolution. Participants will provide blood and saliva samples within 12 hours of injury and undergo a novel MRI scan protocol to assess blood brain barrier integrity, functional networks and white matter microstructure; vestibular/ocular motor screening; cognitive assessment; and balance assessment within 4 days of injury. Notably, the innovative MRI protocol has the potential to set a world standard for imaging after mTBI. Follow-up assessment will be completed by telephone at 2 weeks, 1, 3, 6 and 12 -months after injury to assess post-concussion symptoms, using the Rivermead Post-Concussion Questionnaire (adults), or the Post-Concussion Symptom Inventory (<18years), and quality of life using the Quality of Life after Brain Injury Overall Scale. By collecting data on lifestyle, injury circumstances and pre-existing health factors, and combining this with participant symptoms, we will build a detailed picture of concussion recovery and better direct care, particularly for those identified to be at risk of a delayed recovery.